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There is considerable variation in the half-life of testosterone concentration as reported in the literature, ranging from 10 to minutes. Inactivation of testosterone occurs primarily in the liver. When Testosterone Gel, 1. The potential for testosterone transfer following administration of Testosterone Gel, 1. In one study, 8 male subjects applied a single dose of Testosterone Gel, 1. Two 2 hours after application, female subjects rubbed their hands, wrists, arms, and shoulders to the application site of the male subjects for 15 minutes. Serum concentrations of testosterone were monitored in female subjects for 24 hours after contact occurred. In a second study evaluating transfer of testosterone, 12 male Tamoxifen for sale in UK applied a single dose of Testosterone Gel, 1. Two 2 hours after application, Nolvadex, female subjects rubbed their Nolvadex, wrists, arms, and shoulders to the application site of the male subjects for 15 minutes while the site of application was covered by a t-shirt. A separate study was conducted to evaluate the potential for testosterone transfer from 16 males dosed with Testosterone Gel, 1. Two 2 hours after application to the males on each day, the female subjects rubbed their abdomens for 15 minutes to the abdomen of the males. The males had covered the application area with a T-shirt. In a randomized, 3-way 3 treatment periods without washout period crossover study in 24 hypogonadal men, the effect of showering on testosterone exposure was assessed after once daily application of Testosterone Gel, 1. On the 7th day of each treatment period, hypogonadal men took a shower with soap and water at either 2, 6, or 10 hours after drug application.



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